CLASSIFICATION OF MIXTURES – HEALTH HAZARDS

TS code: AM-L-TS5

OVERVIEW
The lecture describes each of the 10 health hazard classes in accordance with Part 3 of Annex I to CLP, including key terms and definitions, hazard categories for each hazard class and methods of mixtures classification. The criteria for classification of mixtures and the general concentration limits of ingredients that cause classification of mixtures are presented and explained.
Then, for each hazard class, label elements are presented, including pictograms, signal words, standerised hazard and precautionary statements.

LEARNING OBJECTIVES
The aim of the lecture is to introduce trainees to CLP classification rules for health hazards.
The lecture is supplemented with exercises (see AM-E-TS5).
After the training session (lectures and excercises), trainees should:
– get acquainted with the rules of mixtures classification for health hazards according to criteria laid down in part 3 of Annex I to CLP;
– be able to determine concentration limits (specific or generic) for eye damage, eye irritation, skin irritation, skin sensitization, respiratory tract sensitization, carcinogenicity, mutagenicity, reprotoxicity and systemic target organ toxicity of a mixture;
– be able to find substance and specific concentration limits in table 3 of Annex VI to CLP Regulation;
– be able to classify simple mixtures for health risks, taking into account the additive effect of ingredients when required.

CONTENTS

  1. CLASSIFICATION OF SUBSTANCES AND MIXTURES – SHORT INTRODUCTION TO THE TOPIC
  2. HEALTH HAZARD CLASSES
    2.1. Acute toxicity
    2.2. Skin corrosion/ irritation
    2.3. Serious eye damage/ eye irritation
    2.4. Respiratory or skin sensitisation
    2.5. Germ cell mutagenicity
    2.6. Carcinogenicity
    2.7. Reproductive toxicity
    2.8. Specific target organ toxicity – single exposure
    2.9. Specific target organ toxicity – repeated exposure
    2.10. Aspiration hazard